INTRAUTERINE INSEMINATION (IUI)
Intrauterine Insemination (also called IUI and sperm washes) involves placing specially treated or
“washed” sperm directly into a woman’s uterus. This treatment is helpful for both male and female
infertility. Since the sperm is placed beyond the cervix, the sperm avoids the cervical mucus. It is
recommended in patients with
- ovulatory dysfunction (pco)
- mild male factor infertility
- coital issues (ejaculatory dysfunction)
- mild endometriosis
- unexplained infertility
- cervical factor
- HIV / HBsAg discordant couple
- requirement of donor sperm.
The woman’s partner may produce their sperm sample in the comfort of their own home, as long as
the sample is given to the laboratory within 60 minutes, or they can provide it in one of our private
This procedure can be done in a natural cycle in which the patient does not use any medications, or
in combination with oral or injected medications. The patient will undergo cycle monitoring (blood
work and ultrasound on certain key days during her cycle) and when she is showing signs of
ovulation, she will be informed of the best time for the insemination to be done. In some cases,
the physician will “trigger” ovulation with a medication called HCG in order to ensure the proper
Two inseminations are performed, on two consecutive days, ideally one before and one after
ovulation. This procedure is not painful and takes only a few minutes to perform. Afterwards, the
patient is asked to lie down for 10 minutes and she can resume normal activity right away. Fourteen
days later she can return to the clinic for a pregnancy test.
Donor sperm can also be used for males with no sperm, or in the case of single women or same sex
couples. The intrauterine insemination of donor sperm is similar to the aforementioned procedure,
except that it uses an anonymous donor’s sperm.
Please be aware that the cycle success rate in insemination is between 15%-20%. We rarely
recommend more than three cycles because most pregnancies using this technique occur in the first
cycle. If fertilisation does not take place, an appointment is arranged so that the patients can be
advised by our Reproductive Medicine Committee. Our medical team meets to evaluate the clinical
case and inform the couple of their options.